Alpha lipoic acid

As a coenzyme, lipoic acid plays role in two key oxidation removing decarboxylation actions, namely it can catalyze the generation and transfer of acyl group in the pyruvate dehydrogenase complex and α ketoglutarate dehydrogenase complex. Alpha lipoic acid contains the double sulfur five membered ring structure, its electron density is very high, it has the significant ability of electrophilicity and free radicals reaction, so it has antioxidant properties with high value of health care and medical treatment (such as anti fatty liver and lowering plasma cholesterol role). In addition, sulfhydryl of lipoic acid easily take oxidation-reduction reaction, so it can protect the sulfhydryl enzyme from toxicity of heavy metal ion. Lipoic acid is widely distributed in nature, it is particularly rich in liver and yeast cells. In food, lipoic acid always coexists with vitamin B1. It can be synthesized in human body. Human lipoic acid deficiency Has not been found yet.

Qualification:

Item	Specifications	Results
Assay	99.0~101.0%
Art No. AJL0059B	99.7%
Identification(HPLC)	Meets the requirements	Complies
Melting Point	60.0~62.0℃	60.2~61.8℃
Solubility(1N NaOH)	Clear and pale yellow	Complies
Residue on ignition	≤0.10%	0.06%
Heavy metals	≤10ppm	<10ppm
Chloride	≤0.10%	<0.07%
Loss on drying	≤0.2%	0.05%
Specific optical rotation	-1.0~+1.0°	Complies
Related substances(HPLC)
Single impurity	≤0.1%	Complies
6,8-Epitrithiooctanoic acid	≤0.1%	0.08%
Total impurities	≤0.5%	0.14%
Polymers(TLC)	≤2.0%	<2.0%
Residual solvents(GC)
Toluene	≤890ppm
Acetic ether	≤5000ppm	182ppm
Cyclohexane	≤3880ppm	830ppm
Acetone	≤5000ppm	12ppm
Microbiology
Total aerobic count (CFU/g)	≤1000	Complies
Yeasts & Molds (CFU/g)	≤100	Complies
Salmonellas.	Negative	Negative
E. Coli	Negative	Negative
Appearance	Yellowish crystalline powder	Complies

Storage: Store at room(18~25℃) temperature. Protect from moisture and light.

Package:25kg/drum

B group vitamin: In Europe it is drugs used in the treatment of diabetic neuropathy or neurological complications.

Antioxidant: It is known as the "universal antioxidant" as hunter of free radicals, it is the limited essential nutrients to generate energy using sugar class substances by organism. It can be widely used for treatment and prevention of heart disease, diabetes and other diseases. It can effectively enhance the immune system to avoid damage from free radical.

A heavy metal chelating agent: it can inhibit the presenile dementia

A very strong acting force:

It involves in energy metabolism, strengthen the ability of eliminating free radicals of other antioxidants, promote to recover and improve the body to gain muscle and lose fat, it also can improve insulin sensitivity, help to lead creatine into the muscle cells. Lipoic acid is one of the seven anti aging nutrition, it can beautify, activate cells and improve hair growth.

Application: It is mainly used for diabetic neuropathy complication of drug and dietary supplements.

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