Product Name:
|
Arbutin
|
Synonyms:
|
4-Hydroxyphenyl β-D-Glucopyranoside,
Hydroquinone-β-D-glucoside
|
CAS:
|
497-76-7
|
MF:
|
C12H16O7
|
MW:
|
272.25
|
EINECS:
|
207-850-3
|
Arbutin Chemical Properties
|
mp
|
195-198 °C
|
alpha
|
-64 º (c=3)
|
refractive index
|
-65.5 ° (C=4, H2O)
|
storage
|
2-8°C
|
solubility
|
H2O: 50 mg/mL hot, clear
|
Water Solubility
|
10-15 g/100 mL
at 20 ºC
|
Sensitive
|
Hygroscopic
|
Merck
|
14,773
|
BRN
|
89673
|
Stability:
|
Stable.
Hygroscopic - store under dry nitrogen.
|
Usage
|
Arbutin is a
component used in the skin-whitening cosmetics.
|
|
Safety Information
|
Hazard Codes
|
Xn
|
Risk Statements
|
20/21/22-36/37/38
|
Safety Statements
|
22-24/25-36-26
|
WGK Germany
|
3
|
RTECS
|
CE8863000
|
F
|
3-1022-24/25-36-26-23
|
HS Code
|
29389090
|
Introduction:
Arbutin is a
glycoside; a glycosylated hydroquinone extracted from the bearberry plant in
the genus Arctostaphylos; inhibits tyrosinase and thus prevents the formation
of melanin. IC50 value: Target: tyrosinase
Function(s): Antioxidant; Skin-Conditioning
Agent, Lightening agent
Application
Arbutin, a
glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an
inhibitor to identify, differentiate and characterize tyrosinase(s).