You are here:Products>Health product raw material

Nicotinamide mononucleotide (NMN)

  • CAS Number 1094-61-7
  • Molecular Formula C11H15N2O8P
  • Molecular Weight 334.22
  • EC Number 214-136-5
  • Function: a cofactor for processes inside mitochondria, for sirtuins, and for PARP
  • Application: a potential neuroprotective and anti-aging agent
  • Negotiable/
    Tel:
    +86 21 58183719

    Summary

      Nicotinamide mononucleotide ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide.Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). Nicotinamide mononucleotide (NMN) is proved by Harvard scientists to reverse aging process and may be new alternatives to aging, type II diabetes, cancers, muscle wasting and inflammatory diseases within five to ten years.

    Properties

      Properties

      IUPAC name: 3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium
      Other names: Nicotinamide ribonucleoside 5'-phosphate; Nicotinamide D-ribonucleotide;β-Nicotinamide ribose monophosphate; Nicotinamide nucleotide

      CAS-No: 1094-61-7
      Mol. Formula: C11H15N2O8P
      Mol. Weight: 334.22

    Product Detail

      Mechanism of action
      NMN increase the NAD+ level in the body.Then, all the modes of acts of NMN is to be the mechanism of NAD+. β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.


      Application

      Aging

      NAD(+) levels were increased significantly both in muscle and liver by NMN

      NMN-supplementation can induce similar reversal of the glucose intolerance

      NMN intervention is likely to be increased catabolism of fats

      NMN-supplementation does mimic exercise

      DNA Damage

      NMN was able to repair the DNA in cells damaged by radiation.

      Neurological Injury

      NMN treatment protects against cICH-induced acute brain injury

      NMN treatment reduces brain cell death and oxidative stress

      Further research

      This has precipitated dozens of studies since that are focused on investigating

      NMN supplementation to treat cardiovascular disease, diabetes, obesity, life extension,

      cancer, Alzheimer’s disease, Parkinson’s disease, and many more.


      Product List

      Product Name

      Grade

      Purity

      Package

      Nicotinamide mononucleotide

      Food grade

      85%

      100g/ 1Kg/ 5Kg

      95%

      100g/ 1Kg/ 5Kg

      Reagent grade

      95%

      5g/25g

      Standard

      98%

      100mg