Summary
A tetramic acid with antibiotic and cytotoxic activity, and a potent inhibitor of HIV-1 integrase.
The tetramic acid, equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against HIV-1 integrase in vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3 end-processing and strand transfer, as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core.
Price list:
|
Package |
Price（USD） |
|
1MG |
78 |
|
100MG |
Inquiry |
Properties
- Appearance: Lyophilized, Solid
Product Detail
A tetramic acid with antibiotic and cytotoxic activity, and a potent inhibitor of HIV-1 integrase.
The tetramic acid, equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against HIV-1 integrase in vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3 end-processing and strand transfer, as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core.